WebThe bisphosphonate drugs most commonly used in adjuvant treatment are: zoledronic acid, which is given by a drip (infusion) into a vein every 6 months. clodronate, which is … WebDec 31, 2001 · At least 25% of patients with breast cancer develop skeletal metastases, with bone the site of disease producing the greatest morbidity. It is apparent that the bisphosphonates present an important component of the treatment strategy. They are now the treatment of choice in tumour-induced hypercalcaemia, and they can reduce bone …
Use of Bisphosphonates in Patients With Metastatic Bone Disease
WebAs a result, these agents are now considered the standard of care for the treatment of breast cancer patients with bone metastases [17]. ... Costa, L.; Addison, C.L. Adjuvant bisphosphonate treatment for breast cancer: Where are we heading and can the pre-clinical literature help us get there? J. Bone Oncol. 2012, 1, 12–17. 20. Clezardin, P ... WebBisphosphonate drugs. The two drugs used to treat primary breast cancer are: zoledronic acid. sodium clodronate. Bisphosphonates may also be prescribed: for people who are at risk of, or who have, osteoporosis. as treatment for secondary breast cancer in the bone. inamy reed epub
The role of bisphosphonates in breast cancer: Direct effects of ...
WebDec 31, 2001 · In addition to inhibiting bone resorption, bisphosphonates have also been shown to exhibit antitumour effects. In vitro, bisphosphonates inhibit proliferation and … WebMar 14, 2024 · Opinion statement Bisphosphonates are utilized routinely in breast cancer. In metastatic disease with bone involvement, bisphosphonates prevent or delay skeletal-related events and can improve pain control. Different agents have shown benefit compared with placebo or no treatment. WebSodium clodronate is a tablet that’s given to reduce the risk of breast cancer spreading to the bones and other parts of the body. It belongs to a group of drugs called … in a series inverter: