Cisplatin salt wasting

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August undefined, 2024

WebRenal salt wasting syndrome has been described in 17 case reports since 1984. It is a rare side effect of cisplatin that manifests with polyuria, hypovolemia, and hyponatremia, … WebSep 1, 2002 · (6) The mechanism of cisplatin-induced hyponatremia is thought to be mainly renal salt wasting syndrome (RSWS), (7) (8) (9) (10) (11) (12) (13) and sometimes the syndrome of inappropriate...

Profound hyponatremia and dehydration: A case of cisplatin …

WebRenal salt wasting: urine Na will be high. Causes include salt-wasting nephropathy, adrenal insufficiency, cisplatin, and thiazide diuretic use. Euvolemic: Hypothyroidism: check TSH. Glucocorticoid deficiency: check AM cortisol. WebCisplatin is an intercalating agent that induces apoptosis of cancer cells, and it has been the most widely used drug in the first-line chemotherapy. However, the increase in cisplatin-resistant cancer cells has become a major obstacle in clinical management of cancers (Amable, 2016 ). bis crush weapons

Tubulointerstitial Injury Associated With Chemotherapeutic …

WebCisplatin is a well-known chemotherapeutic agent that can be associated with hyponatremia. Mechanisms of cisplatin-induced hyponatremia include renal salt wasting … WebNational Center for Biotechnology Information WebSIADH, renal salt-wasting syndrome, and salt loss caused by vomiting and/or anorexia, should be diagnosed as accurately as possible in future studies. ... Alhosaini MN, Patel A. Cisplatin-induced renal salt wasting syndrome. South Med J. 2010;103(8):793–799. 5. Raftopoulos H. Diagnosis and management of hyponatremia in cancer patients. bis crush osrs

National Center for Biotechnology Information

WebSalt wasting Cisplatin Azacitidine Syndrome of inappropriate antidiuresis Cyclophosphamide Vincristine Nephrogenic diabetes insipidus Cisplatin Ifosfamide Magnesium wasting Cetuximab, panitumumab Cisplatin Crystal nephropathy Methotrexate Acute interstitial nephritis Anti-CTLA-4 antibody WebMay 19, 2024 · Rarely, cisplatin-related hyponatremia may result from Renal Salt Wasting Syndrome ( 33 ). Hypernatremia can also develop with cisplatin due to acquired nephrogenic diabetes insipidus with ensuing … dark brown varnishWebJan 25, 2012 · Hyponatremia associated with syndrome of inappropriate secretion of antidiuretic hormone (SIADH) or renal salt-wasting syndrome (RSWS) after platinum-based chemotherapy is not uncommon. However, no reports of RSWS following taxane monotherapy have been previously published. dark brown varnish wood

"WebCisplatin induces both inflammation and vascular injury, which further promotes kidney injury. In addition to AKI, cisplatin causes proximal tubulopathy, salt wasting, loss of urinary concentrating ability, and magnesium wasting. View chapter Purchase book T cells in kidney injury and regeneration Li Li, ... " - Cisplatin salt wasting

Cisplatin salt wasting

Central Diabetes Insipidus and Cisplatin-Induced Renal Salt Wasting ...

WebCisplatin-induced renal salt wasting requiring over 12 liters of 3% saline replacement. Case Rep Nephrol 2024; 2024:8137078 Cadacio C, Pham PT, Bhasin R, Kamarzarian A, Pham PC. Multiple electrolyte and metabolic emergencies in a single patient. Case Rep Nephrol 2024:4521319 WebWe diagnosed this clinical condition as renal salt-wasting syndrome (RSWS) on the basis of dehydration and high urinary sodium excretion at the onset. In the second course of chemotherapy, CDDP was replaced with carboplatin (CBDCA); consequently, hyponatremia was not observed.

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WebFeb 1, 2016 · The marked urinary losses of sodium in combination with a negative sodium balance led to the diagnosis of cisplatin-induced renal salt wasting syndrome (RSWS). The subsequent clinical...

WebThe possibility of Cisplatin induced renal salt wasting was considered. The patient was started on Fludrocortisone 0.1mg twice daily, oral salt tablets 1g QID, sodium bicarbonate tablets 650mg TID and normal saline at 150ml/h. During his five-day hospital course, his renal parameters steadily improved, and his serum sodium improved from 124 mEq ... Web42%–100% of patients depending on total cisplatin dose and length of exposure. Hypomagnesemia and renal magnesium wasting may persist for up to 6 years after initial dose (5). Renal salt wasting syndrome has been reported in up to 10% of patients, manifesting as hyponatremia and severe ortho-static hypotension in the setting of high …

WebFeb 1, 2016 · Cisplatin may produce renal salt wasting causing symptomatic orthostatic hypotension and hyponatremia associated with abnormalities of the renin-aldosterone … WebDifferential diagnosis of hyponatremia induced by cisplatin-containing chemotherapy: syndrome of inappropriate secretion of antidiuretic hormone (SIADH) or renal salt …

WebCisplatin induced renal salt wasting was considered. The patient was started on Fludrocortisone 0.1 mg twice daily, oral salt tablets 1 g QID, sodium bicarbonate tablets …

WebCisplatin is a potent antineoplastic agent derived from platinum and commonly used in the treatment of head ... both water restrictions and sodium supplementation may be … bis cscWebNov 1, 2003 · In 1988, Hutchison et al reported profound urinary sodium wasting in 7 of 70 patients treated with cisplatin over an 18- month period in 1 institution. 1 All the patients were men with carcinomas (including 1 patient with SCLC) and presented 2-4 months after starting cisplatin-based therapy with signs of vol- ume depletion, urinary salt wasting ... bis csc cloudWebMar 1, 2024 · Cisplatin may produce renal salt wasting causing symptomatic orthostatic hypotension and hyponatremia associated with abnormalities of the renin-aldosterone … biscsc pmjay csccloudWebCisplatin is a potent antineoplastic agent derived from platinum and commonly used in the treatment of head ... both water restrictions and sodium supplementation may be appropriate when differentiating between diagnoses of renal salt wasting syndrome and syndrome of inappropriate antidiuretic hormone secretion. Fed Pract. 2024 December;38(12 ... dark brown vanity top bathroomWebCisplatin is a well-known chemotherapeutic agent that can be associated with It is known to be associated with a multitude of renal disorders including acute kidney injury with reduced glomerular... dark brown velvet throw pillowWebCisplatin is known to induce Fanconi syndrome and renal salt wasting (RSW). RSW typically only requires transient normal saline (NS) support. We report a severe RSW case that required 12 liters of 3% saline. A 57-year-old woman with limited stage small cell cancer was admitted for cisplatin (80 mg/m 2) and etoposide (100 mg/m 2) therapy. dark brown vintage tall buffet tableWebFeb 16, 2024 · severe or ongoing nausea and vomiting; vision problems, pain behind your eyes; hearing problems, ringing in your ears; pain, redness, swelling, or skin … dark brown vest for women