Cullin 3 antibody
WebAnti-Cullin 3 antibody produced in rabbit (Anti-CUL3); ~ 1.0mg/mL, affinity isolated antibody, buffered aqueous solution; Suitable for indirect immunofluorescence; Cullin 3 … WebNov 16, 2024 · Abundance of PD-L1, the ligand of the anti-cancer immunotherapy target PD-1, is negatively regulated by poly-ubiquitination via the cyclin D–CDK4/cullin 3–SPOP axis and PD-1 blockade treatment ...
Cullin 3 antibody
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WebThe cullin family proteins are scaffold proteins for the Ring finger type E3 ligases, participating in the proteolysis through the ubiquitin-proteasome pathway. Humans express seven cullin proeins: CUL1-3, CUL4A, CUL4B, CUL5, and CUL7. Each cullin protein can form an E3 ligase similar to the prototype Ring-type E3 ligase Skp1-CUL1-F-box complex. WebJan 1, 2013 · Cullin 3 as a therapeutic target. Through selective degradation of these substrates, E3 ligases regulate many biological processes and are considered as …
WebMar 29, 2024 · Cullin3 (CUL3) suppresses proliferation, migration and phenotypic transformation of PDGF-BB-stimulated vascular smooth muscle cells and mitigates inflammatory response by repressing Hedgehog signaling pathway. Xiang Y, et al. Bioengineered, 2024 Dec. PMID 34699319, Free PMC Article WebView Rabbit Polyclonal anti-Cullin 3 Antibody (NBP2-88799). Validated Applications: WB. Validated Species: Human. Skip to main content Support: 1-888-506-6887 Items in Cart …
WebHome; Products. Featured Collections. Recombinant Rabbit Monoclonal Antibodies; IHC/Pathology Antibodies; KO Validated Antibodies; Antibodies. Primary Antibodies WebMar 24, 2024 · KCTD7 is a component of the Cullin-3 E3 ligase complex and interacts with calpains. To identify candidate KCTD7 targets, we performed tandem affinity purification (TAP) followed by liquid chromatography-tandem mass spectrometry (LC-MS/MS) in HEK293 cell line stably expressing human KCTD7 fused to streptavidin- and calmodulin …
WebMay 12, 2024 · MLN4924, a neddylation inhibitor of Cullin-Ring E3 ligases, dramatically reduced the proliferation of tumor cells, especially CUL3-overexpressing cells, which showed that BECN1 degradation mediated by CUL3 could be an effective therapeutic target for breast cancer. Results BECN1 protein level is regulated through the ubiquitin … philippines open to travelWebCullin 3 antibody LS-B6963 is an unconjugated rabbit polyclonal antibody to human Cullin 3 (CUL3) (aa618-667). Validated for IHC and WB. philippines open yetWebCullin 3 Antibody (NB100-58787): Novus Biologicals Cited in 1 publications. View Rabbit Polyclonal anti-Cullin 3 Antibody (NB100-58787). Validated Applications: IHC, IHC-P, IP, WB (-). Validated Species: Human, Mouse, Rat + more. Skip to main content Support: 1-888-506-6887 Items in Cart (0) [X] Quick Order Account COVID-19 Research Tools philippines operaWebOct 27, 2024 · Treatment with DI-591 selectively converts cellular cullin 3 into an un-neddylated inactive form with no or minimum effect on other cullin members. ... anti-DCN1 (GWB-E3D700) antibody from GenWay ... philippines operations support contract ivWebBoster Bio Anti-Cullin 3/CUL3 Antibody catalog # PA1939. Tested in WB applications. This antibody reacts with Human, Mouse, Rat. Supplied as 100μg/vial in Lyophilized form … trundle wallpaperWebGeneral notes. This product is a recombinant monoclonal antibody, which offers several advantages including: - High batch-to-batch consistency and reproducibility. - Improved … philippines opera musicWebCullin 3 Antibodies. Antibodies that detect Cullin 3 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry, … trundle twin