High theophylline levels

Author: eans

August undefined, 2024

WebMar 18, 2010 · Theophylline (3-methyxanthine) has been used to treat airway diseases for over 70 years. It was originally used as a bronchodilator but the relatively high doses required are associated with frequent side effects, so its use declined as inhaled β2-agonists became more widely used. WebIn most individuals, a plasma-theophylline concentration of 10–20 mg/litre (55–110 micromol/litre) is required for satisfactory bronchodilation, although a lower plasma …

Theophylline - PMC - National Center for Biotechnology Information

WebNo food or liquid (other than water) was allowed for 4 hours after which a standard lunch was served. Mean peak theophylline serum levels (C max) was 6.69 mcg/mL and mean time of peak serum concentration (T ... In patients with high theophylline clearance and half-lives of about 4 to 5 hours, such as children age 1 to 9 years, the trough serum ... WebJan 14, 2024 · Check with your doctor immediately if any of the following side effects occur while taking theophylline: Incidence not known Chest pain or discomfort dizziness fainting fast, slow, or irregular heartbeat increase in urine volume lightheadedness persistent vomiting pounding or rapid pulse seizures shakiness daniel thropp

National Center for Biotechnology Information

WebTheophylline in overdose can cause vomiting (which may be severe and intractable), agitation, restlessness, dilated pupils, sinus tachycardia, and hyperglycaemia. More … WebDec 24, 2024 · Aminophylline is FDA-approved to treat reversible airway obstruction due to asthma or other chronic lung diseases. This activity illustrates the indications, mechanism of action, pharmacokinetics, and … WebHigh-carbohydrate, low-protein diets can increase theophylline activity and side effects. Sustained-release forms of theophylline should be taken on an empty stomach and should not be crushed or chewed. Liquid and non-sustained release theophylline products are best taken on an empty stomach, but they may be taken with food if stomach upset occurs. daniel thrown in the lions den

Chronic obstructive pulmonary disease: Theophylline

High theophylline levels

Theophylline - StatPearls - NCBI Bookshelf

WebMar 1, 2024 · At serum Theophylline concentrations > 20 mcg/mL, both the frequency and severity of adverse reactions increase. In general, maintaining peak serum Theophylline concentrations between 10 mcg/mL and 15 … WebJul 18, 2024 · In high doses, theophylline can cause irritability, tremors and seizures as well as tachycardia, cardiac arrhythmias and sudden death. With the development of safer, better tolerated and more effective inhaled …

Did you know?

WebSixty patients with theophylline toxicity were hospitalized during a 2-year period. Eleven patients had hypercalcemia; their calcium levels returned to normal as theophylline levels … WebAug 31, 2024 · High-risk cases include the following: Acute overdose with theophylline levels higher than 80 mcg/mL Chronic toxicity with levels higher than 40 mcg/mL Patients …

WebToo much theophylline can be life-threatening. Symptoms of too much theophylline include: Vomiting, heartburn, and belly pain. Rapid heart rate or other changes in heart rhythm. … WebSep 21, 2024 · If administering aminophylline, the dose should increase by 25% (as aminophylline is 79% to 86% theophylline). Dose calculations …

WebSerum theophylline levels were measured in 23 consecutive asthmatics presenting to the ER in an acute attack. 15 (68%) had therapeutic levels (above 10 mcg/ml) and 2 had toxic levels (above 20 mcg/ml), prior to receiving the standard … WebAug 31, 2024 · high blood sugar--increased thirst, increased urination, dry mouth, fruity breath odor. Serious side effects may be more likely in older adults. Common side effects …

WebApr 1, 2024 · fast, slow, or irregular heartbeat increase in urine volume lightheadedness persistent vomiting pounding or rapid pulse seizures shakiness Get emergency help …

WebFeb 10, 2024 · The reference therapeutic ranges of theophylline are listed below. Reference ranges of theophylline in the treatment asthma vary by age, as follows: Adults: 5-15 µg/mL. Children: 5-10 µg/mL. The... The assessment and diagnosis of exercise-induced bronchoconstriction is made … daniel thrasher perfect pitchWebTheophylline levels In most individuals a plasma theophylline of between 10-20mg/litre is required for satisfactory bronchodilation; however, a lower plasma theophylline … birthday apps for freeWebTherapeutic levels: 4 to 12 mcg/ml [SI: 17 to 51 micromole/L] Note: 4 to 8 mcg/mL if patient is receiving other anticonvulsants. Half-life: 8 - 60 hours in adults Epoxide metabolite: 25 to 43 hours (active metabolite) Time to … daniel thurmanWebHigh blood theophylline levels can lead to symptoms of toxicity (see below). Therefore, theophylline blood levels are monitored periodically during treatment to assure achievement of optimal and safe levels. The initial dose is 300-600 mg once daily or as a divided dose for 3 days. The maintenance dose is 400-600 mg daily. daniel thurstonWebJul 22, 2024 · The molecular formula of anhydrous theophylline is C 7 H 8 N 4 O 2 with a molecular weight of 180.17. Theo-24 is available as capsules intended for oral administration, containing 100 mg, 200 mg, 300 mg, or 400 mg of anhydrous theophylline per capsule, in an extended-release formulation which allows a 24-hour dosing interval for … daniel thrown into the lion\u0027s denWebB. Estimate Mr B’s theophylline level at the time of fitting C. How long after stopping Nuelin will Mr B’s theophylline be within the therapeutic range? [Population data: clearance = 0.04 L/hr/kg & volume of distribution = 0.48 L/kg. CHF reduces theophylline clearance by 50%. F … daniel thrown into the lion\\u0027s denWebToxic side effects of elevated theophylline levels range from minor symptoms to life-threatening complications. We investigated the incidence of life-threatening events in … birthday arch hike