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WebJan 10, 2024 · Fast or slow heartbeats. Very stiff muscles, high fever, sweating, or tremors. Jaundice (yellowing of the skin or eyes) The following side effects may get better over time as your body gets used to the medication. Let your doctor know immediately if you continue to experience these symptoms or if they worsen over time. WebPromethazine: Antidopaminergic effect due to blocking mesolimbic dopamine receptors and alpha-adrenergic receptors in the brain; antihistaminic effect due to blocking H1-receptors. Dextromethorphan: Acts on cough center in medulla; derivative of levorphanol. Promethazine. Onset: 20 min. Duration: 4-6 hr. Bioavailability: 25% (PO) Protein Bound: 93% high minded complex helmet
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